This is a video from the folks at Homemade Movies of the Family Guy intro recreated shot-for-shot with humans. I hope you know I'm being honest when I say that is not how I imagined the cartoon characters would look like as real people. I dunno, maybe they didn't have time to hold a proper casting call. Also, why is Brain sitting in that ghost's lap? I heard pets usually respond negatively to the supernatural, although my fish act like they couldn't care less. They sure seem to love that rum-drinking skeleton though.
Keep going for this video and a side-by-side comparison with the original.
Thanks to Sea, who better not be filled with sharks.